Trouble running a python/poetry flask app under apache / wsgi - apache

Question

I've written a flask app using poetry and want to run it under the control of apache and wsgi. I've spent hours scouring documentation and experimenting and I've learned a lot but still have not figured it out. Here is the blow by blow:
The app works when I run it directly from the command line in poetry:
python3 ./otproject/otpflask/src/run.py
* Serving Flask app 'teacher' (lazy loading)
* Environment: production
WARNING: This is a development server. Do not use it in a production deployment.
Use a production WSGI server instead.
* Debug mode: on
* Running on http://127.0.0.1:5000/ (Press CTRL+C to quit)
* Restarting with stat
* Debugger is active!
* Debugger PIN: 141-706-196
^Crpsalas#otproject:~/mydev/development$
According to poetry, my venv is here:
$ poetry env info
VirtualEnv
Python: 3.8.10
Implementation: CPython
Path: /home/rpsalas/.cache/pypoetry/virtualenvs/otproject-Yy_WWjvb-py3.8
Valid: True
System
Platform: linux
OS: posix
Python: /usr
Then I configure my apache mod_wsgi as follows
<VirtualHost *:80>
WSGIDaemonProcess test python-home=/home/rpsalas/.cache/pypoetry/virtualenvs/otproject-Yy_WWjvb-py3.8
WSGIProcessGroup test
WSGIApplicationGroup %{GLOBAL}
WSGIScriptAlias /test /var/www/test/test.wsgi
<Directory /var/www/test/src/>
Order allow,deny
Allow from all
</Directory>
</VirtualHost>
The wsgi python script test.wsgi looks like this:
#!/usr/bin/env python
from otproject.otpflask.teacher import app as application
But when I restart the apache service it fails horribly:
Fatal Python error: init_fs_encoding: failed to get the Python codec of the filesystem encoding
Python runtime state: core initialized
ModuleNotFoundError: No module named 'encodings'
Current thread 0x00007f99756e4c40 (most recent call first):
<no Python frame>
[Sun Jul 25 20:35:24.503068 2021] [wsgi:warn] [pid 154900:tid 140297076886592] (13)Permission denied: mod_wsgi (pid=154900): Unable to stat Python home /home/rpsalas/.cache/pypoetry/virtualenvs/otproject-Yy_WWjvb-py3.8. Python interpreter may not be able to be initialized correctly. Verify the supplied path and access permissions for whole of the path.
Python path configuration:
PYTHONHOME = '/home/rpsalas/.cache/pypoetry/virtualenvs/otproject-Yy_WWjvb-py3.8'
PYTHONPATH = (not set)
program name = 'python3'
isolated = 0
environment = 1
user site = 1
import site = 1
sys._base_executable = '/usr/bin/python3'
sys.base_prefix = '/home/rpsalas/.cache/pypoetry/virtualenvs/otproject-Yy_WWjvb-py3.8'
sys.base_exec_prefix = '/home/rpsalas/.cache/pypoetry/virtualenvs/otproject-Yy_WWjvb-py3.8'
sys.executable = '/usr/bin/python3'
sys.prefix = '/home/rpsalas/.cache/pypoetry/virtualenvs/otproject-Yy_WWjvb-py3.8'
sys.exec_prefix = '/home/rpsalas/.cache/pypoetry/virtualenvs/otproject-Yy_WWjvb-py3.8'
sys.path = [
'/home/rpsalas/.cache/pypoetry/virtualenvs/otproject-Yy_WWjvb-py3.8/lib/python38.zip',
'/home/rpsalas/.cache/pypoetry/virtualenvs/otproject-Yy_WWjvb-py3.8/lib/python3.8',
'/home/rpsalas/.cache/pypoetry/virtualenvs/otproject-Yy_WWjvb-py3.8/lib/python3.8/lib-dynload',
]